A different view of COVID-19

A different view of COVID-19

Queen카지노 게임 컬렉션s 카지노게임사이트 researcher Mona Kanso develops new way of looking at novel coronavirus that could help uncover treatments

By Anne Craig

November 2, 2020

Share

Queen카지노 게임 컬렉션s 카지노게임사이트 researcher Mona Kanso has developed a new and unique way of looking at viruses, including SARS-CoV-2, the virus that causes COVID-19. By sculpting the coronavirus particle from tiny beads, and then applying the laws of fluid physics to each and every bead, Kanso calculates the properties of the coronavirus from its shape. While the full potential of this new method is still being realized, researchers expect it will accelerate the path to developing a treatment and, eventually, finding a cure. 

카지노 게임 컬렉션We know of no other way to calculate the transport properties of a virus from its shape,카지노 게임 컬렉션 Kanso says. 

SARS-CoV-2 is a spherical shell covered with spikes called peplomers, which the virus uses to attach itself to the cells it infects. Since the virus cannot move itself, it relies on the random thermal motion of its fluid surroundings, to rotate, to align its spikes with its target on a cell. Once attached, the virus can infect the cell and then spread. 

카지노 게임 컬렉션Think of it like a jittery spaceship docking with a space station,카지노 게임 컬렉션 explains Kanso, (PhD chemical engineering candidate, Vanier Canada Research Scholar). 카지노 게임 컬렉션The jittery virus must align two of its adjacent spikes, just so, with the binding sites so it can attach to the cell. It relies on kinetic molecular energy from the fluid to rotate itself into position.카지노 게임 컬렉션 

This research opens the door to understanding drugs that might prevent cell binding by interfering with virus rotational diffusion. It also deepens scientists카지노 게임 컬렉션 understanding of viral cellular infection. 

Kanso collaborated with her Queen카지노 게임 컬렉션s summer trainee, Jourdain Piette, along with their Queen카지노 게임 컬렉션s advisor, Professor Jeffrey Giacomin, sheltered in place on his sabbatical leave on the campus of the 카지노게임사이트 of Nevada, Reno, and with Dr. Giacomin카지노 게임 컬렉션s UNR host, Professor James Hanna. 

카지노 게임 컬렉션In this work, we uncover a better way of looking at viruses,카지노 게임 컬렉션 says Kanso. 카지노 게임 컬렉션Like any engineering problem, trying to solve it without understanding it, takes forever. This coronavirus is spiked for more than one reason. There is the obvious mechanical function of target attachment. But its spikes are also controlling its own jitter, by receiving energy from the fluid, to help it dock with its targets. This coronavirus is a far more formidable adversary than it looks.카지노 게임 컬렉션 

The next step is to explore how the triangular bulb on the tip of each coronavirus spike affects infection. Also, under the microscope, not all of the coronaviruses are spherical. Called pleomorphism, no one knows how this affects the alignment and attachment probability.  

The research is published, and freely available, in .